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锰元素(赖氨酸锰Manganese Lysinate)在动物代谢中的关键作用

发表时间:2025-06-14 18:36

锰(赖氨酸锰Manganese Lysinate)作为动物体内不可或缺的重要元素,深度参与葡萄糖、蛋白质、尿素等物质的循环代谢过程。其主要作用机制是调节代谢过程中酶的活力,在饲料中合理添加锰(赖氨酸锰Manganese Lysinate),对维持动物体的正常代谢意义重大。相关研究表明,在日粮中补充有机锰和无机锰,能有效增加羊羔肝脏中锰的沉积量,同时提升锰超氧化物歧化酶(Mn-SOD)和精氨酸酶的活性。精氨酸酶作为锰的依赖性酶,在肝脏尿素循环代谢的最后环节发挥着关键作用。丙酮酸羧化酶是糖异生过程中的关键酶,能将丙酮酸羧化为草酰乙酸,它是三羧酸循环和糖异生的连接转换点,且其激活高度依赖锰,这使得锰直接参与糖异生,并间接参与三羧酸循环。此外,崔德汶的研究显示,添加 485mg/kg 的氨基酸锰可提高绵羊瘤胃中丙酸生成量,为肝脏糖异生提供有力支持。孙昱等的研究则发现,随着日粮中锰含量增加,血液中谷丙转氨酶含量显著升高,饲喂锰含量为 60mg/kg 的饲料,对辽宁绒山羊蛋白质代谢提升效果显著。

锰元素(赖氨酸锰Manganese Lysinate)在动物代谢中的关键作用

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The key role of the manganese element (lysine manganese lysinate) in animal metabolism

As an indispensable and important element in animals, manganese (manganese lysine) is deeply involved in the circulation and metabolism of glucose, protein, urea and other substances. Its main mechanism of action is to regulate the activity of enzymes in the metabolic process, and the reasonable addition of manganese (Manganese lysine) to the feed is of great significance to maintain the normal metabolism of animals. Relevant studies have shown that supplementation of organic manganese and inorganic manganese in the diet can effectively increase the amount of manganese deposition in the liver of lambs, and increase the activities of manganese superoxide dismutase (Mn-SOD) and arginase. Arginase, as a manganese-dependent enzyme, plays a key role in the final link of hepatic urea cycle metabolism. Pyruvate carboxylase is a key enzyme in the process of gluconeogenesis, which can carboxylize pyruvate into oxaloacetate, which is the junction transition point between the tricarboxylic acid cycle and gluconeogenesis, and its activation is highly dependent on manganese, which makes manganese directly involved in gluconeogenesis and indirectly involved in the tricarboxylic acid cycle. In addition, Cui Dewen's study showed that the addition of 485mg/kg of manganese amino acid can increase the production of propionic acid in the rumen of sheep, providing strong support for hepatic gluconeogenesis. Sun Yu et al.'s study found that with the increase of manganese content in the diet, the content of alanine aminotransferase in the blood increased significantly, and feeding a feed with a manganese content of 60mg/kg had a significant effect on the protein metabolism of Liaoning cashmere goats.

The key role of the manganese element (lysine manganese lysinate) in animal metabolism

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